Why this test?
An increase in the activity of pancreatic amylase in the blood without a change in the activity of salivary amylase serves as confirmation of the pathology of the pancreas.
For example, with acute pancreatitis, its activity in the blood can increase to 90% of the total activity of amylase.
For the diagnosis of pancreatitis in the postoperative period, when the activity of total amylase is increased.
If pathology of the salivary glands, ovaries or bronchi is suspected.
In what cases is it prescribed
When confirming the diagnosis of "acute" or "chronic pancreatitis".
Suspected diseases of the salivary glands and ovaries.
Amylase is a digestive enzyme capable of breaking down carbohydrates. The largest amount of amylase is found in the salivary and pancreatic glands. Amylase, which is produced in the pancreas - pancreatic amylase (P-type) - is part of pancreatic juice. From the pancreas, pancreatic juice containing lipase enters the duodenum through the pancreatic duct, where it helps digest food. Amylase of the salivary glands - salivary amylase (S-type) - transforms food starch in the oral cavity.
Normally, a small amount of amylase circulates in the blood. At the same time, about 60% is salivary amylase (S-type), and the remaining 40% is pancreatic amylase. When there is damage to the pancreas, as in pancreatitis, or if the pancreatic duct is blocked by a stone or tumor, pancreatic amylase (P-type) begins to enter the bloodstream in larger amounts. There is no increase in the activity of salivary amylase.