β-Cross Laps test
Why this test?
To detect the level of β-Cross Laps in the blood.
In what cases is it prescribed?
- To establish the activity of resorptive processes in bone tissue.
- To diagnose the osteoporosis.
- Monitoring and evaluation of the osteoporosis therapy effectiveness.
- To assess the effectiveness of surgical treatment of an adenoma or a malignant tumor of the parathyroid glands.
- The conduct and control hormone replacement therapy in case of women’s menopause.
- In case of chronic kidney failure.
Information about the test
β-Cross Laps is a highly specific marker of bone tissue resorption. Type 1 collagen accounts for more than 90% of the organic bone matrix. As a result of constant remodeling of bone tissue, this collagen can be destroyed, while its fragments enter the blood. One of which is the C-terminal telopeptide. Alpha-aspartic acid, which is part of C-terminal telopeptides, is converted into beta form (β-CrossLaps). These isomerized telopeptides are specific degradation products of collagen type 1, the level of which increases in case of increased bone resorption patients. They can be specific only for bone tissue. Their determination in the blood has an important advantage, because they do not undergo further catabolism and are excreted in the urine
