Insulin-like growth factor II (oncomarker of adrenal cortex)

Why this test?

For differential diagnosis of carcinoma and adenoma of the adrenal cortex.

In what cases is it prescribed?

Suspected adrenal cortex cancer. If a tumor is detected, tests may be ordered to determine the type of tumor and assess the response to treatment. For patients who have undergone a course of treatment, the analysis can be prescribed for the timely diagnosis of a possible relapse.

Test information

Insulin-like growth factor is a hormone involved in controlling the production of growth hormone (somatotropin). This growth factor is synthesized starting from the period of intrauterine development and throughout life. The peak of IGF-2 production occurs during the period of embryogenesis (development of the fetus before birth). After birth, the production of IGF-2 does not stop, but remains at a low level. It can increase due to some oncological pathologies. First of all, with a tumor of the cortex of the adrenal glands. Therefore, the analysis for insulin-like growth factor II is used as a marker for this type of cancer.