Lab24 menu synevo
Warsaw
Are you in Warsaw?
Yes Change
City choosing helps us to find up-to-date information about tests, their prices, and methods of material testing in your city
Lab24 telephone +48 573 569 057
  • EN
  • UA
  • PL
Lab240

Cholinesterase (serum)

50 zł
Readiness of result: from 2 day
Choose a nurse's home visit at a special price or get a -15% discount on laboratory visits
Teleconsultation with a doctor on the selection of tests and results
89 zł More
General practitioners
General practitioners
Therapist
How to prepare for testing?
Do not eat 12 hours before the study
Do not eat 12 hours before the study
Eliminate physical and emotional stress for 30 minutes before the study
Eliminate physical and emotional stress for 30 minutes before the study
Do not smoke for 30 minutes before the study
Do not smoke for 30 minutes before the study
Why this test?

To check a patient who has had contact with pesticides containing organophosphorus substances - they can inhibit cholinesterase and pseudocholinesterase activity.
Symptoms appear suddenly in the case of acute poisoning or may occur gradually, as chronic exposure to these substances occurs. Penetration of insecticides into the body can occur by inhalation, ingestion or skin contact.

To detect hereditary pseudocholinesterase deficiency. Sometimes enzyme deficiency can be inherited due to genetic variations of the enzyme. Pseudocholinesterase is necessary for the body to inactivate succinylcholine, a muscle relaxant that is usually used during surgery. In patients with low activity or a defective form of pseudocholinesterase after anesthesia, the effect of medications may be prolonged, causing prolonged muscle paralysis and suffocation.

In what cases is it prescribed?

Periodically, those who use organophosphorus substances in agriculture or in the chemical industry.

In the assessment of acute poisoning by harmful substances that can cause neuromuscular damage. Symptoms of poisoning vary depending on the substance, its quantity and the way it enters the body: headache, dizziness, nausea, increased lacrimation and salivation, sweating.

In very severe poisoning, additional symptoms appear: vomiting, diarrhea, darkening of the eyes or blurred vision due to narrowing of the pupils, muscle weakness, convulsive twitching, impaired coordination of movements, slowed breathing, which leads to respiratory failure and the need for artificial lungs ventilation.

Before surgery, if close relatives of the patient have ever had prolonged paralysis and suffocation after the use of succinylcholine.

Test information

Cholinesterase is an enzyme necessary for the functioning of the nervous system.

There are two types of cholinesterase in the body: acetylcholinesterase, which is present in red blood cells, as well as in the lungs, spleen, nerve endings, and gray matter of the brain, and pseudocholinesterase (butyrylcholinesterase), which is found in blood serum, liver, muscle, pancreas, heart, and white matter of the brain. Acetylcholinesterase is involved in the transmission of nerve impulses by breaking down acetylcholine, a chemical that transmits signals through nerve cell endings.

A decrease in the activity of acetylcholinesterase leads to the accumulation of acetylcholine in nerve endings. This, in turn, leads to excessive irritability of nerve cells.

Pseudocholinesterase is necessary for the breakdown and metabolism of toxins and medicinal substances.


Have you hard time trying to understand the lab test results?
Use our new service of interpreting lab test results by a doctor
Lab24 backpack
Order now
With this test buy
Haptoglobin 60 zł
Sodium (Na) 26 zł
Glucose 21 zł
Lab24 assistant
Hi! Need help?
Yes
×

Quick order

More details
Send request