Creatinine in urine (daily urine)
Why this test?
- To assess the functional state of the kidneys;
- To monitor patients with existing kidney pathology.
In what cases is it prescribed?
- During the preventive examination of the patient.
- If there is a suspicion of existing kidney pathology or there are obvious symptoms of renal dysfunction (the presence of swelling on the face, around
the eyes or lower legs, ankles, urinary disorders, etc.)
- In case of acute or chronic diseases accompanied by kidney damage (diabetes mellitus, arterial hypertension, vasculitis, etc. ).
- In monitoring the treatment of patients with kidney disease.
- To study the amount of biological substances in the urine.
Creatinine is the end product of the breakdown of creatine and creatine phosphate excreted by the kidneys. The kidneys secrete creatinine constantly. Its absorption back into the blood from the urine practically does not occur. Therefore, by determining the level of creatinine in the urine, you can estimate the filtration capacity of the kidneys. The concentration of creatinine in blood is several tens and hundreds of times lower than in urine.
The amount of creatinine excreted in the urine per day is relatively constant, which is proportional to its formation in 24 hours. This indicator is influenced by factors such as muscle mass, gender, age. Therefore, men will excrete more creatinine than women and children.