Why this test?
This test is intended to determine the individual dose of drugs based on lamotrigine, as well as to control dosage in order to assess the level of toxicity and control the removal of drugs from the body.⠀
When is it prescribed?
This study is intended to determine the individual dose of the drug for the patient, as well as to control the dosage throughout the entire period of treatment. In case of combination with other drugs. In the presence of physiological or pathological reasons for changes in pharmacokinetics - age characteristics, pregnancy, liver disease, kidney disease, gastrointestinal tract. When changing the brand/manufacturer of the drug.
This significantly increases the efficiency and safety of therapy and allows you to achieve success in each specific case
Information about the test
Lamotrigine is an anticonvulsant drug, the mechanism of action of which is associated with the blocking of potential-dependent sodium channels of the presynaptic membranes of neurons in the phase of slow inactivation and with the inhibition of excessive release of glutamate (an amino acid that plays a significant role in the development of an epileptic attack). Exceeding the dose of the drug can cause side effects (headache, dizziness, drowsiness, sleep disturbance, feeling of fatigue, aggressiveness, confusion, nausea, impaired liver function, leukopenia, thrombocytopenia). Allergic reactions: rash on the skin (usually maculopapular), angioedema, Stevens-Johnson syndrome, toxic epidermal necrolysis, lymphadenopathy.
Therefore, this study is designed to minimize the occurrence of side effects during therapy with this drug.